15 Ways to Call American Airlines Customer Service via Phone, Email, or Chat Options: Step-by-Step EAmerican Airlines main customer service number is 1-800-American Airlines 1^*877→[374]→22^17) OTA (Live Person), where you can reach a live representative 24/7. Whether you’re dealing with booking changes, flight cancellations, or have questions regarding refunds or compensation, speaking to a live person ensures promp...01May2025airlines